Class ForkCoordinator

Coordinates replication fork progression and strand synthesis activities.

Constructors

constructor

Properties

actualStepsTaken allEvents dna fork laggingStrand leadingStrand organism replisome

Methods

advanceFork completeReplication finalizeReplication getAllEvents getCurrentState getDNA getEventsByType getOrganism getStatistics initializeReplication isComplete

Constructors

constructor

Properties

Private actualStepsTaken

actualStepsTaken: number = 0

Private Readonly allEvents

allEvents: ReplicationEvent[] = []

Private Readonly dna

dna: DNA

DNA sequence being replicated

Private Readonly fork

fork: ReplicationFork

Replication fork managing position and progress

Private Readonly laggingStrand

laggingStrand: LaggingStrandSynthesis

Private Readonly leadingStrand

leadingStrand: LeadingStrandSynthesis

Private Readonly organism

organism: OrganismProfile

Organism profile for biological parameters

Private Readonly replisome

replisome: Replisome

Methods

advanceFork

completeReplication

Private finalizeReplication

getAllEvents

getCurrentState

getDNA

getEventsByType

getOrganism

getStatistics

  • getStatistics(): {
        actualSteps: number;
        eventCounts: {
            dnaSynthesis: number;
            ligation: number;
            primerRemoval: number;
            primerSynthesis: number;
            proofreading: number;
            unwind: number;
        };
        fork: {
            completion: number;
            isComplete: boolean;
            position: number;
        };
        laggingStrand: {
            activeFragments: number;
            completedFragments: number;
            isActive: boolean;
            synthesizedLength: number;
            totalFragments: number;
        };
        leadingStrand: {
            isActive: boolean;
            position: number;
            speed: number;
            synthesizedLength: number;
        };
        totalEvents: number;
    }

  • Gets statistics about the replication process.

    Returns {
        actualSteps: number;
        eventCounts: {
            dnaSynthesis: number;
            ligation: number;
            primerRemoval: number;
            primerSynthesis: number;
            proofreading: number;
            unwind: number;
        };
        fork: {
            completion: number;
            isComplete: boolean;
            position: number;
        };
        laggingStrand: {
            activeFragments: number;
            completedFragments: number;
            isActive: boolean;
            synthesizedLength: number;
            totalFragments: number;
        };
        leadingStrand: {
            isActive: boolean;
            position: number;
            speed: number;
            synthesizedLength: number;
        };
        totalEvents: number;
    }

    Replication statistics

    • actualSteps: number
    • eventCounts: {
          dnaSynthesis: number;
          ligation: number;
          primerRemoval: number;
          primerSynthesis: number;
          proofreading: number;
          unwind: number;
      }
      • dnaSynthesis: number
      • ligation: number
      • primerRemoval: number
      • primerSynthesis: number
      • proofreading: number
      • unwind: number
    • fork: {
          completion: number;
          isComplete: boolean;
          position: number;
      }
      • completion: number
      • isComplete: boolean
      • position: number
    • laggingStrand: {
          activeFragments: number;
          completedFragments: number;
          isActive: boolean;
          synthesizedLength: number;
          totalFragments: number;
      }
      • activeFragments: number
      • completedFragments: number
      • isActive: boolean
      • synthesizedLength: number
      • totalFragments: number
    • leadingStrand: {
          isActive: boolean;
          position: number;
          speed: number;
          synthesizedLength: number;
      }
      • isActive: boolean
      • position: number
      • speed: number
      • synthesizedLength: number
    • totalEvents: number

initializeReplication

isComplete

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