Class DNALigase

DNA Ligase - Joins Okazaki fragments by forming phosphodiester bonds.

Hierarchy (view full)

Enzyme
- DNALigase

Index

Constructors

Properties

isActive position type

Methods

advance canOperate getSpeed ligate moveTo setActive toString

Constructors

constructor

new DNALigase(position, isActive?): DNALigase
Parameters
- position: number
- isActive: boolean = true
Returns DNALigase
Overrides Enzyme.constructor
- Defined in src/model/replication/enzyme/DNALigase.ts:15

Properties

isActive

isActive: boolean = true

Whether enzyme is currently active

position

position: number

Current position of the enzyme (0-based)

`Readonly` type

type: EnzymeType

Type of enzyme

Methods

advance

advance(distance): number
Advances the enzyme by the specified distance.
Parameters
- distance: number
  Distance to advance in base pairs
Returns number
New position
Inherited from Enzyme.advance
- Defined in src/model/replication/enzyme/Enzyme.ts:52

canOperate

canOperate(position): boolean
Checks if this enzyme can operate at the given position.
Parameters
- position: number
  Position to check
Returns boolean
True if enzyme can operate at this position
Overrides Enzyme.canOperate
- Defined in src/model/replication/enzyme/DNALigase.ts:24

getSpeed

getSpeed(organism): number
Gets the operating speed of this enzyme for the given organism.
Parameters
- organism: OrganismProfile
  Organism profile for speed calculation
Returns number
Speed in base pairs per second
Overrides Enzyme.getSpeed
- Defined in src/model/replication/enzyme/DNALigase.ts:19

ligate

ligate(fragmentId): ReplicationEvent
Ligates two adjacent DNA fragments.
Parameters
- fragmentId: string
  ID of fragment being ligated
Returns ReplicationEvent
Replication event for ligation
- Defined in src/model/replication/enzyme/DNALigase.ts:35

moveTo

moveTo(position): void
Moves the enzyme to a specific position.
Parameters
- position: number
Returns void
Inherited from Enzyme.moveTo
- Defined in src/model/replication/enzyme/Enzyme.ts:70

setActive

setActive(active): void
Sets the enzyme's active state.
Parameters
- active: boolean
Returns void
Inherited from Enzyme.setActive
- Defined in src/model/replication/enzyme/Enzyme.ts:63

toString

toString(): string
Gets a string representation of this enzyme.

Returns string
Inherited from Enzyme.toString
- Defined in src/model/replication/enzyme/Enzyme.ts:80