Interface PolyadenylationSite

Represents a polyadenylation site with detailed information about the polyadenylation signal and surrounding regulatory elements.

interface PolyadenylationSite {
    cleavageSite?: number;
    downstreamDSE?: GenomicRegion;
    position: number;
    signal: string;
    strength: number;
    upstreamUSE?: GenomicRegion;
}

Properties

cleavageSite?: number

Predicted cleavage position (11-23 bp downstream of signal)

downstreamDSE?: GenomicRegion

Downstream sequence elements (U-rich and GU-rich) that enhance efficiency

position: number

Position of the polyadenylation signal in the sequence

signal: string

The actual signal sequence found (e.g., "AAUAAA", "AUUAAA")

strength: number

Strength score based on signal type and context (0-100)

upstreamUSE?: GenomicRegion

Upstream sequence elements (U-rich and UGUA motifs) that enhance efficiency