Class Promoter

constructor

• new Promoter(transcriptionStartSite, elements, name?): Promoter

• Creates a new Promoter.

  Parameters

  • transcriptionStartSite: number

    Position of TSS in genomic coordinates
  • elements: PromoterElement[]

    Array of PromoterElements that define this promoter
  • Optional name: string

    Optional name for this promoter

  Returns Promoter

  Example

  const promoter = new Promoter(
      1000, // TSS at position 1000
      [tataBox, initiatorElement],
      "beta-globin-promoter"
  );
  Copy

Readonly elements

Optional Readonly name

Readonly transcriptionStartSite

getElementPosition

• getElementPosition(element): number

• Gets the genomic position of a promoter element.

  Parameters

  • element: PromoterElement

    The PromoterElement to locate

  Returns number

  Genomic position of the element (TSS + element.position)

getElementsByName

• getElementsByName(elementName): PromoterElement[]

• Gets all elements of a specific type from this promoter.

  Parameters

  • elementName: string

    Name of the element type to find (e.g., "TATA", "Inr")

  Returns PromoterElement[]

  Array of matching PromoterElements

getElementsByPosition

• getElementsByPosition(): PromoterElement[]

• Gets all promoter elements sorted by their genomic position.

  Returns PromoterElement[]

  Array of elements sorted from upstream to downstream

getStrengthScore

• getStrengthScore(): number

• Calculates a strength score for this promoter based on its elements. This is a simplified scoring system - real promoter strength depends on many factors.

  Returns number

  Numeric score representing promoter strength (higher = stronger)

hasElement

• hasElement(elementName): boolean

• Checks if this promoter contains a specific type of element.

  Parameters

  • elementName: string

    Name of the element type to check for

  Returns boolean

  true if promoter contains at least one element of this type

toString

• toString(): string

• Gets a string representation of this promoter.

  Returns string

  String describing the promoter and its elements